Total Synthesis of Paecilomycin B.
نویسندگان
چکیده
Starting from the glucose-derived δ-lactone and the functionalized aryl bromide, the first total synthesis of naturally occurring paecilomycin B was achieved via functionalized aryl-β-C-glycoside synthesis using 2,4,6-triisopropylphenyllithium under Barbier-type reaction conditions and ring-closing metathesis as the key steps.
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ورودعنوان ژورنال:
- Organic letters
دوره 17 12 شماره
صفحات -
تاریخ انتشار 2015